The first phase of the U.K. synthetic human genome project has successfully completed, realizing key steps in chromosome synthesis. The work has demonstrated a multistep method for transfecting mouse ...

Today, genomics is saving countless lives and even entire species, thanks in large part to a commitment to collaborative and open science that the Human Genome Project helped promote. Twenty-five ...

David Botstein, Princeton’s Anthony B. Evnin ‘62 Professor of Genomics, Emeritus, and an emeritus professor of molecular biology and the Lewis-Sigler Institute for Integrative Genomics, died on Feb.

A human cell is a Rube Goldberg machine like no other, full of biological chain reactions that make the difference between life and death. Understanding these delicate relationships and how they go ...

An illustration of multicolored tangle of threads within a small black sphere. A 3D illustration shows DNA packaged into the nucleus, scientists with the 4D Nucleome project are now building accurate ...

Single-cell RNA-seq (scRNA-seq) has spent the past decade maturing into a foundational technology. Over that time, the technology has both laid the foundation for building cell atlases and allowed ...

Scientists are launching an ambitious global effort to map the “human exposome” — the lifelong mix of environmental and chemical exposures that drive most diseases. Backed by new partnerships with ...

How much of our genome really matters? Some argue that because most of our DNA is active, it must be doing something important. Others say even random DNA would be highly active. This has now been put ...

Twenty-five years ago today, on July 7, 2000, the world got its very first look at a human genome — the 3 billion letter code that controls how our bodies function. Posted online by a small team at ...