Using a deep learning model to analyze the composition of large muscles on MRI, German researchers found that the proportions ...

Myofibrillar myopathy type 6 (MFM6) is a rare genetic muscle disorder that leads to severe muscle weakness and a drastically shortened life expectancy due to a disruption in muscle protein regulation.

Findings show that impaired autophagy leads to muscle degeneration, inflammation, and mitochondrial defects, while ...

A series of recent physiology studies span from rare disease mechanisms to space-based biomedical advances. Findings include a new mouse model for myofibrillar myopathy type 6 that identifies ...

Following the US Food and Drug Administration (FDA) announcement on the phasing out of animal testing, the drug development industry has welcomed a wave of new approach methodologies (NAMs). However, ...