Space exploration activity has been increasing. In turn, researchers are more interested than ever in uncovering more about how space travel affects human health and the progression of disease.

Myofibrillar myopathy type 6 (MFM6) is a rare genetic muscle disorder that leads to severe muscle weakness and a drastically shortened life expectancy due to a disruption in muscle protein regulation.

A cell therapy preserves muscle structure and function in laboratory mice with a type of disease similar to Duchenne muscular dystrophy, according to new research from the Smidt Heart Institute at ...

The mechanism of skeletal muscle contraction is a process that relies on calcium signaling. However, the physiological role of calcium-induced calcium release (CICR) through the ryanodine receptor ...

Findings show that impaired autophagy leads to muscle degeneration, inflammation, and mitochondrial defects, while ...

For more than 30 years, scientists have studied how the myogenic determination gene number 1 (MYOD) protein binds DNA to modify the gene expression of muscle stem cells. Similar to the instant kung fu ...

A series of recent physiology studies span from rare disease mechanisms to space-based biomedical advances. Findings include ...

Muscle cells contain their own circadian clocks and disrupting them with shift work can have a profound impact on aging, according to the results of a preclinical study carried out by Jeffrey Kelu, ...

In myofibrillar myopathy type 6 (MFM6), the sarcomeres—the smallest units of the muscle fiber responsible for muscle movement and tension—break down. This is triggered by a defective BAG3 protein ...