For the first time, scientists have grown a tiny, three-dimensional model of the earliest developmental stages of the human central nervous system in the lab. The new model is a type of organoid — a ...

The first organized stem cell culture model that resembles all three sections of the embryonic brain and spinal cord, and produces a full model of the early stages of the human central nervous system, ...

Fluorescent micrographs showing increased neurite outgrowth from a human spinal cord organoid treated with fast-moving “dancing molecules” (left) compared to one treated with slow-moving molecules ...

Injuries in the central nervous system (CNS)—such as those in the spinal cord—trigger glial scar formation, which inhibits nerve regeneration from healthy neurons surrounding the damage. This results ...

Today McLain is chair of the Department of Physical Medicine and Rehabilitation, holder of the Robert B. Kyle Professorship and Chair in Rehabilitation Medicine, and director of the UAB Spinal Cord ...

Usage and reporting of analgesia in animal models of spinal cord injury (SCI) have been sparse and requires proper attention. The majority of experimental SCI research uses rats as an animal model.

Phase 1b/2a trial of NervGen’s lead compound, NVG-291, is based upon unprecedented, peer-reviewed animal studies demonstrating pronounced functional recovery from spinal cord injury “The ability of ...