The infamous "0x80070643 - ERROR_INSTALL_FAILURE" issue is back with one of the new Windows 10 updates KB5048239. Thankfully, there is a fix. This past week, alongside the Patch Tuesday updates for ...
I'm betting you could do a fresh install from the latest media creation tool and it will take care of it. I would hope so anyway. I think that is what I would do in your situation, backup everything, ...